In the American continent, it is mainly a jungle zoonosis (but it can be acquired in semi-desert or cold regions) transmitted by sand flies mainly of the genera It is endemic in Asia, Africa, the Americas, and the Mediterranean region. Leishmaniasis is a disease with a worldwide distribution it is found in about 89 countriesĥ. In Mexico, the most characteristic form is the cutaneous-chondral form Leishmania involved and the immune response of the hostģ.
The clinical features include a broad range of manifestations with different degrees of severity that depend on the species of It is found in all continents except OceaniaĤ and is endemic in circumscribed geographic areas in Northeastern Africa, Southern Europe, the Middle East, Southeastern Mexico, and Central and South America.
According to the World Health Organization (WHO), leishmaniasis is one of the seven most important tropical diseases and it represents a serious world health problem that presents a broad spectrum of clinical manifestations with a potentially fatal outcomeģ. Lutzomyia (Europe, Northern Africa, the Middle East, Asia, and part of South America) exceptionally, transmission has also been reported as a laboratory accidentġ. Leishmaniasis is a tropical and subtropical disease caused by an intracellular parasite transmitted to humans by the bite of a sand fly, mainly
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